- B Complex Vitamin
- Complexe de Vitamines B
- Vitamin B-2
- Vitamin G
- Vitamina B2
- Enriched flour
- Green vegetables
- Riboflavin is used for preventing low levels of riboflavin (riboflavin deficiency)
- Cervical cancer
- Migraine headaches
- Treating riboflavin deficiency
- Muscle cramps
- Burning feet syndrome
- Carpal tunnel syndrome
- Blood disorders such as congenital methemoglobinemia and red blood cell aplasia.
- Some people use riboflavin for eye conditions including
- Eye fatigue
- Increasing energy levels
- Boosting immune system function
- Maintaining healthy hair, skin, mucous membranes, and nails
- Slowing aging
- Boosting athletic performance
- Promoting healthy reproductive function
- Canker sores
- Alzheimer's disease
- Liver disease
- Sickle cell anemia
- Treating lactic acidosis brought on by treatment with a class of AIDS medications called NRTI drugs
Effectiveness of Vitamin B2
- 2- Cataracts, an eye disorder
- People who eat more riboflavin as part of their diet seems to have a lower risk of developing cataracts.
- Taking supplements containing riboflavin plus niacin seems to help prevent cataracts.
- 3- High amounts of homocysteine in the blood (hyperhomocysteinemia)
- Some people are unable to convert the chemical homocysteine into the amino acid methionine.
- People with this condition, especially those with low riboflavin levels, have high amounts of homocysteine in the blood.
- Taking riboflavin for 12 weeks seems to reduce homocysteine levels by up to 40% in some people with this condition.
- Certain antiseizure drugs can increase homocysteine in the blood.
- Taking riboflavin along with folic acid and pyridoxine seems to lower homocysteine levels by 26% in people with high homocysteine levels due to antiseizure drugs.
- 4- Migraine headaches
- Taking high-dose riboflavin (400 mg/day) seems to significantly reduce the number of migraine headache attacks.
- Taking riboflavin does not appear to reduce the amount of pain or the amount of time a migraine headache lasts.
- Lower doses of riboflavin (200 mg/day) do not seem to reduce the number of migraine headache attacks.
- 5- Lactic acidosis (a serious blood-acid imbalance) in people with acquired immunodeficiency syndrome (AIDS).
- Riboflavin may be useful for treating lactic acidosis in patients with acquired immunodeficiency syndrome (AIDS) caused by drugs called nucleoside analog reverse transcriptase inhibitors (NRTI).
- 6- Preventing cervical cancer.
- Increasing riboflavin intake from dietary and supplement sources, along with thiamine, folic acid, and vitamin B12, may decrease the risk of developing precancerous spots on the cervix.
- 7- Liver cancer
- Taking riboflavin along with niacin may reduce the risk of liver cancer in people less than 55 years-old.
- Vitamin B2 does not seem to reduce the risk of liver cancer in older people.
- 8- White patches inside the mouth (oral leukoplakia)
- Low blood levels of riboflavin are linked with an increased risk of oral leukoplakia.
- Riboflavin supplements for 20 months do not seem to prevent or treat oral leukoplakia.
- 9- Sickle cell disease
- Taking riboflavin for 8 weeks improves iron levels in people with low iron levels due to sickle cell disease.
- Riboflavin does not seem to improve levels of hemoglobin, the iron-containing protein in the blood.
- Riboflavin may be safe for most people when taken by mouth.
- In some people, riboflavin can cause the urine to turn a yellow-orange color.
When taken in high doses, riboflavin might cause diarrhea, an increase in urine, and other side effects.
Precautions & Warnings
- Riboflavin may be safe for pregnant or breast-feeding women when taken in the amounts recommended.
- The recommended amounts are 1.4 mg per day for pregnant women and 1.6 mg per day in breast-feeding women.
- Riboflavin is may be safe when taken by mouth in larger doses, short-term.
- Riboflavin is safe when taken at a dose of 15 mg once every 2 weeks for 10 weeks.
- Riboflavin absorption is decreased in people with these conditions.
Vitamin B2 interactions with medication
Moderate Interactions (Be cautious with this combination)
- Riboflavin might decrease the amount of tetracyclines that the body can absorb.
- Taking riboflavin along with tetracyclines might decrease the effectiveness of tetracyclines.
- To avoid this interaction, take riboflavin 2 hours before or 4 hours after taking tetracyclines.
- Some tetracyclines include demeclocycline (Declomycin), minocycline (Minocin), and tetracycline (Achromycin).
Minor Interactions (Be watchful with this combination)
- Some drying medications can affect the stomach and intestines.
- Taking these drying medications with riboflavin (vitamin B2) can increase the amount of riboflavin that is absorbed in the body.
- But it's not known if this interaction is important.
- Some medications for depression can decrease the amount of riboflavin in the body.
- This interaction is not a big concern because it only occurs with very large amounts of some medications for depression.
- Riboflavin is broken down by the body.
- Phenobarbital might increase how quickly riboflavin is broken down in the body.
- It is not clear if this interaction is significant.
- Probenecid (Benemid) can increase how much riboflavin is in the body.
- This might cause there to be too much riboflavin in the body.
- But it's not known if this interaction is a big concern.
Interactions with Herbs and Supplements
- Psyllium reduces absorption of riboflavin from supplements in healthy women.
- It isn't clear whether this occurs with dietary riboflavin, or whether it's really important to health.
- A form of boron, called boric acid, can reduce the solubility of riboflavin in water.
- This might reduce the absorption of riboflavin.
- In people with a condition called methylenetetrahydrofolate reductase (MTHFR) deficiency, taking folic acid might make riboflavin deficiency worse.
- Folic acid might lower blood levels of riboflavin in people with this condition.
- Riboflavin supplements may improve the way iron supplements work in some people who don't have enough iron.
- This effect is probably important only in people with riboflavin deficiency.
Interactions with Foods
- Absorption of riboflavin supplements may be increased when taken with food.
- For treating low levels of riboflavin (riboflavin deficiency) in adults: 5-30 mg of riboflavin (Vitamin B2) daily in divided doses.
- For preventing migraine headaches: 400 mg of riboflavin (Vitamin B2) per day. It may take up to three months to get best results.
- For preventing cataracts: a daily dietary intake of approximately 2.6 mg of riboflavin (Vitamin B2) has been used. A combination of 3 mg of riboflavin (Vitamin B2) plus 40 mg of niacin daily has also been used.
- The daily recommended dietary allowances (RDAs) of riboflavin (Vitamin B2) are:
- Infants 0-6 months: 0.3 mg
- Infants 7-12 months: 0.4 mg
- Children 1-3 years: 0.5 mg
- Children 4-8 years: 0.6 mg
- Children 9-13 years: 0.9 mg
- Men 14 years or older: 1.3 mg
- Women 14-18 years: 1 mg
- Women over 18 years: 1.1 mg
- Pregnant women: 1.4 mg
- Breastfeeding women: 1.6 mg